Diagnostic value of additional histopathological fascia examination in idiopathic inflammatory myopathies
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چکیده
منابع مشابه
Diagnostic value of MHC class I staining in idiopathic inflammatory myopathies.
BACKGROUND Identification of mononuclear cellular infiltrates in skeletal muscle tissue is the histological cornerstone of the diagnosis of idiopathic inflammatory myopathy (IIM). However, these infiltrates are not always present. OBJECTIVE To determine whether MHC class I antigen expression on the sarcolemma, which is absent in normal muscle tissue, is upregulated in IIM and could serve as a...
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INTRODUCTION The purpose of this study was to evaluate and compare the serum levels and local expression of resistin in patients with idiopathic inflammatory myopathies to controls, and to determine the relationship between resistin levels, inflammation and disease activity. METHODS Serum resistin levels were determined in 42 patients with inflammatory myopathies and 27 healthy controls. The ...
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Autoimmune response to nuclear and cytoplasmic autoantigens is detected in about 60-80% of patients affected with idiopathic inflammatory myositis such as polymyositis (PM), dermatomyositis (DM) and inclusion body myositis (IBM). Some of the serum autoantibodies are shared with other autoimmune diseases (myositis-associated antibodies MAA) and some of them are unique to myositis (myositis-speci...
متن کاملChemokines in idiopathic inflammatory myopathies.
The idiopathic inflammatory myopathies (IIM) represent a heterogeneous group of acquired muscle diseases. The three best-studied subgroups: dermatomyositis (DM), polymyositis (PM), and sporadic inclusion body myositis (IBM), differ considerably both clinically and pathophysiologically. DM is a chiefly humoral endotheliopathy often associated with characteristic skin manifestations. In PM and IB...
متن کاملClassification of Idiopathic Inflammatory Myopathies
15 DOI 10/1007/978-1-60327-827-0_2, © Humana Press. a part of Springer Science + Business Media, LLC 2009 Abstract Although it has been long recognized that inflammatory muscle disease of unknown etiology may present clinically and respond to therapy in a variety of ways, our approaches regarding how to best classify or divide these entities into more understandable groups of patients has evolv...
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ژورنال
عنوان ژورنال: European Journal of Neurology
سال: 2019
ISSN: 1351-5101,1468-1331
DOI: 10.1111/ene.14027